PAKISTAN SOCIETY OF PHARMACOGNOSY & NATURAL THERAPY
PAKISTAN SOCIETY OF PHYTOPHARMACOLOGY & THERAPEUTICS
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STUDY OF HYPOLIPIDEMIC EFFECT OF HERBAL AND HOMEOPATHIC
ANTIDIABETIC DRUGS IN ALLOXAN INDUCED DIABETIC RABBITS


Obaidullah1, Ikramullah Khanl, Zafar Iqbaf, Wilayat Ahmadi and Noor Muhammad Shah2 'Faculty of Pharmacy, Gomal University, Dera Ismail Khan, Pakistan 2Department of Pharmacy, University of Peshawar, Peshawar, Pakistan

 

ABSTRACT: Diabetes mellitus is often associated with hyperlipidemia, which may lead to coronary heart disease. Commercially available herbal and homeopathic drugs claimed to be useful for the treatment of diabetes mellitus are evaluated for hypolipidemic effect in alloxan induced diabetic rabbits. The glibenclamide and gliclazide were used as standard drugs. The herbal drug Dolabi significantly (p<0.05) reduces blood total lipids level while Dawai Ajeeb Ziabetus failed to alter blood total lipids level of alloxan induced diabetic rabbits. All homeopathic drugs viz. acid phos, syz jambol and uranium nitricum did not reduce blood total lipids level.

KEY WORDS: Diabetes mellitus, herbal, homeopathic, alloxan induced diabetic rabbits, blood total lipids level.