PAKISTAN SOCIETY OF PHARMACOGNOSY & NATURAL THERAPY
PAKISTAN SOCIETY OF PHYTOPHARMACOLOGY & THERAPEUTICS
PAKISTAN SOCIETY OF PHARMACOGNOSY & NATURAL THERAPY*** PAKISTAN SOCIETY OF PHYTOPHARMACOLOGY & THERAPEUTICS
 
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SENSITIVITY OF FINE NEEDLE ASPIRATION CYTOLOGY IN CERVICAL LYMPH
NODES IN NASOPHARYNGEAL CARCINOMA


Syed Qaiser Husain Naqvi, Syed Iqbal Husain*, Abdul Lateef Ansari** and Azam Husain Yousfani**
*Patrzology Departmellt, Peoples Medical College Nawabs/zah *Department of ENT, Peoples Medical College Nawabshah
**Department of Pathology, Peop
les Medical College Nawabshah

ABSTRACT: To see the sensitivity of fine needle aspiration cytology (FNAC) in cervical lymph nodes in patients of nasopharyngeal carcinoma (NPC). 32 patients having cervical lymphadenopathy were divided in two groups: A and B.Group A includes 23 patients which were undiagnosed cases of NPC, out of these 19 patients have ENT symptoms and 04 patients having only cervical l¥Mphadenopathy without any ENT symptom. Group B includes 09 post irradiated patients of NPC having detectable cervical lymphadenopathy.Fine needle aspiration (FNA) was performed with 22 gauge needle attached with 10 mI syringe and 128 smears were prepared (04/patient), stained with haemotoxyIen and eosin (H&E) stain. Small surgical tissue biopsies were also taken to correlate the histological findings with cytological findings of the smear of same patient. Close resemblance was found between H&Estained cytological smears and tissue sections by observing under light microscope. The commonest pattern observed was undifferentiated carcinoma. FNAC of cervical lymph nodes is an important tool in the diagnosis of NPC, especially in those patients who have no any ENT symptom. FNAC is also helpful in the follow up of post irradiated patients.

KEY WORDS: FNAC, Cervical lymphadenopathy, NPC.