PAKISTAN SOCIETY OF PHARMACOGNOSY & NATURAL THERAPY
PAKISTAN SOCIETY OF PHYTOPHARMACOLOGY & THERAPEUTICS
PAKISTAN SOCIETY OF PHARMACOGNOSY & NATURAL THERAPY*** PAKISTAN SOCIETY OF PHYTOPHARMACOLOGY & THERAPEUTICS
 
MENU
     
   
   
   
   
   
   
   
   
   
 
 
 

SEMEN AND HORMONAL ANALYSIS OF PATIENTS HAVING

AZOOSPERMIA AND OLIGOZOOSPERMIA Mubashir A. Shaikh, Muhammad
Shoaib Khan, Aftab Turabi, K.A Shakoor, Irshad AU
and Musa Kaleem Balooch . .
Depwtment of Clinical Pathology and Depwtment of Medicine,
Jinnah Postgraduate Medical Centre, Karachi, Pakistan' Department
of Chemistly, Gomal University D. I. Kllall, Pakistan

ABSTRACT:
The possible changes were determined in semen quality of azoospermic and oligozoospermic Pakistani infertile men, over a period of 4 years (1998 to 2002), through Semen examination, which is one of the most valuable diagnostic methods in male infertility. Retrospective analysis of semen volume, liquefaction time, pH and sperm concentration were carried out for 150 men trom infertile couples in which 50 cases (33.33%) showed azoospermia (A), 50 cases (33.33%) had oligozoospermia (B), 20 cases (13.33%) were asthenozoospermic (C) and 30 cases (20%) were found to be normozoospermic (D). The linear regression analysis shows a decrease in semen volume in groups A and B, mean semen volume (m1) for the four respective studied groups being 1.5:t 0.4,1.7:t 2, 2.5:1:0.1 and 2.4:t0. The mean liquefaction time (min) was 37.5:t 0.7, 28.7:t3.7, 18.5 :to.7 and 18.6:t 3.6 in groups A, B, C and D respectively, showing linear increase in groups A and B. pH did not vary much amongst groups and ranged fi:om 7.0 - 8.5. Mean sperm concentration was 0.0,6.7:t 1.7,45.3 :t8.8 and 86.8:t7.5 millionlm1 in groups A, B.C and D. The hormonal profile showed normal or low levels of testosterone while FSH and ill levels indicated inverse/negative correlation to sperm concentration, wh~reas no significant relationship between serum prolactin and semen density was detectable between different groups.

KEY WORDS: Azoospermia, Oligozoospermia, Asthenozoospermia, ill, FSH, Prolactin, Testosterone, Infertile, Male, Pakistan.