PAKISTAN SOCIETY OF PHARMACOGNOSY & NATURAL THERAPY
PAKISTAN SOCIETY OF PHYTOPHARMACOLOGY & THERAPEUTICS
PAKISTAN SOCIETY OF PHARMACOGNOSY & NATURAL THERAPY*** PAKISTAN SOCIETY OF PHYTOPHARMACOLOGY & THERAPEUTICS
 
MENU
     
   
   
   
   
   
   
   
   
   
 
 
 
STUDY OF HYPOGLYCEMIC EFFECT OF HERBAL AND
HOMEOPATHIC ANTIDIABETIC DRUGS IN NORMAL AND
ALLOXAN INDUCED DIABETIC RABBITS


Obaidullahl*, Ikramullah Khan\ Zafar IqbaI2**and Wilayat AhmadI
1 Faculty of Pharmacy, Gomal University, Dera Ismail Khan, Pakistan 2
Department of Pharmacy, University of Peshawar, Peshawar, Pakistan

 

ABSTRACT:
Commercially available herbal and homeopathic drugs claimed to be used for the treatment of diabetics are evaluated for blood glucose level in normal and alloxan induced diabetic rabbits. The glibenclamide and glicalazide were used as standard drugs. The herbal drugs, dolabi and dawai ajeeb ziabitus, showed the significant (p < 0.05) decrease in the blood glucose level in normal rabbits. In alloxan induced diabetic animals the significant decrease was for very short period of time compared with the normal rabbits. The single dose administration of homeopathic drugs, i.e. acid phos, syz jambol and uranium nitricum failed to reduce the blood glucose level both in normal and alloxan induced diabetic rabbits. However, the oral administration of single dose daily of acid phos and syz jambol significantly reduced the blood glucose level on 7th days after 2 h and 4h, respectively, post administration of the drugs.